Vitamin D and VDR gene polymorphism (FokI) in epithelial ovarian cancer in Indian population
نویسندگان
چکیده
منابع مشابه
Vitamin D and VDR gene polymorphism (FokI) in epithelial ovarian cancer in Indian population
INTRODUCTION Vitamin D deficiency and vitamin D receptor (VDR) gene polymorphism, FokI, is reported to increase the risk of many cancers. Role of vitamin D and its receptor polymorphisms in ovarian cancer has not been clearly defined. OBJECTIVE To study the levels of serum vitamin D and occurrence of vitamin D receptor gene polymorphism (FokI) in cases of ovarian cancer. MATERIAL AND METHOD...
متن کاملLack of association between FokI polymorphism in vitamin D receptor gene (VDR) & type 2 diabetes mellitus in the Tunisian population
BACKGROUND & OBJECTIVES The impact of several environmental and genetic factors on diabetes is well documented. Though the association between the vitamin D receptor (VDR) gene polymorphisms and type 2 diabetes mellitus (T2DM) has been analyzed in different ethnic groups, the results have been inconsistent. The aim of this study was to evaluate the possible association between VDR FokI polymorp...
متن کاملAre there Relationships between the VDR-FokI Polymorphism and Vitamin D and the Insulin Resistance in Non-melanoma Skin Cancer (NMSC) Patients? A Protocol for Case-control Studies
Background and Objectives: Evidence indicate relationships between the sunlight exposure, vitamin D status and non-melanoma skin cancer (NMSC) risk. Vitamin D receptor (VDR) polymorphisms have been linked to metabolic changes in insulin resistance and various cancers. The purpose of this study is to investigate relationships between the sunlight exposure and the NMSC risk. Furthermore, relation...
متن کاملVitamin D Receptor (VDR) Gene Variants and Susceptibility to BPH in a North Indian Population
BPH is most commonly encountered non-neoplastic prostatic disease. Despite its high prevalence and major impact on quality of life of patient, the aetio-pathogenesis and risk factor of BPH are not clear. The only risk factor of BPH established in several independent and longitudinal studies is aging. BPH lacks established genetic markers for determining disease susceptibility. Vitamin D primari...
متن کاملIs there any association between a vitamin D receptor gene polymorphism (FokI) and pemphigus vulgaris?
Background: Pemphigus vulgaris (PV) is an autoimmune bullous disease of the skin and mucous membranes caused by activation and proliferation of T cells, production of Th2 cytokine profile and pathogenic antibodies. Vitamin D is a probable immunodeviator to Th2, which its actions are mediated through the vitamin D receptor (VDR). FokI is the only single nucleot...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Ovarian Research
سال: 2013
ISSN: 1757-2215
DOI: 10.1186/1757-2215-6-37